For treatment-resistant depression that hasn't responded to antidepressants, SPRAVATO® offers a new path.
SPRAVATO® (esketamine) is FDA-approved for treatment-resistant depression — a fast-acting, REMS-certified treatment administered in a clinical setting with proven results.
SPRAVATO® is covered by most major insurance plans
Most major commercial insurers, Medicare, and Medicaid cover SPRAVATO® for patients who meet clinical criteria for treatment-resistant depression. Our coordinators handle all verification and prior authorization.
- We verify your patients' benefits before their first appointment
- Most patients pay little to no out-of-pocket cost
- We handle REMS enrollment and prior authorization on your behalf
What is SPRAVATO®?
SPRAVATO® (esketamine) is an FDA-approved nasal spray for treatment-resistant depression and major depression with acute suicidal ideation. It works on glutamate receptors, providing rapid relief for patients who haven't responded to other medications.
Ketamine-derived nasal spray
SPRAVATO® is an esketamine nasal spray taken in a certified healthcare setting under medical supervision. It is self-administered under direct observation.
Acts on glutamate receptors for rapid relief
Unlike SSRIs that target serotonin, SPRAVATO® works on NMDA glutamate receptors, enabling faster neuroplasticity and antidepressant effects — often within hours to days.
REMS-certified clinical setting required
SPRAVATO® must be administered in a certified REMS setting with 2-hour post-dose monitoring. Our partner practices are fully REMS-enrolled, which is managed by Everbright.
What to expect during treatment
Real patients. Real results.
Hear from patients who found rapid relief through SPRAVATO® after years of struggling with treatment-resistant depression.
It didn't make me a new person. It helped me become Ben.
Results may vary. Patient stories are shared with consent.
Bring SPRAVATO® to your practice
Everbright embeds a complete, REMS-certified SPRAVATO® service line into your practice — infrastructure, trained staff, prior authorization, and patient acquisition.
What Everbright handles so you don't have to
Eligible patient identification and activation
Treatment-eligible patients are automatically identified using clinical and payor-specific criteria and engaged and educated through multiple channels.
Clinical infrastructure (optional)
Equipment, trained staff, templates, and clinical protocols embedded directly into your practice.
Prior authorization
End-to-end prior authorization management with 2x industry approval rates.
Billing and compliance (optional)
Full RCM management so your team stays focused on care.
Outcomes tracking
Structured clinical data across PHQ-9, GAD-7, and treatment response metrics.